Report Overview

The global spatial genomics & transcriptomics market is projected to reach USD 232.5 million by 2022, with a compound annual growth rate (CAGR) of 12.2% expected from 2023 to 2030. The integration of spatial genomics & transcriptomics in the pharmaceutical industry has gained significant traction, with increasing demand driven by its applications in drug discovery and development, particularly for conditions such as neurodegenerative disorders and cancer. The potential of spatial genomic analysis as a cancer detection tool is growing, while advancements in fourth-generation sequencing technologies are anticipated to propel further growth in the market.

According to a recent study published in the Frontiers Journal, October 2022, spatial transcriptomics holds significant promise in uncovering intricate spatial locations such as tumor interfaces and tertiary lymphoid structures. The research also suggests that this technology has considerable potential for refining pathology diagnosis and identifying novel cancer prognostic variables, which is expected to drive market growth.

The growth of the market can be attributed to several key drivers, including the growing need for personalized medicine solutions, advancements in biomarker identification for accurate diagnosis, and significant investments in research and development initiatives. The rising incidence of chronic diseases, particularly cancer, not only boosts diagnostic rates but also creates opportunities for advanced diagnostics. According to data from the National Center for Health Statistics, in the U.S., there were 1,918,030 new cancer cases reported in 2022, resulting in 609,360 fatalities due to cancer.

Technology Insights

In 2022, the spatial transcriptomics segment emerged as the primary revenue driver, commanding a substantial 79.0% market share due to its widespread adoption by researchers seeking high-resolution insights into gene expression within tissue architecture—something traditional genomic tools lack. The surge in automated sequencing technologies has enhanced the efficiency and affordability of nucleic acid sequencing, especially at the single-cell level, further cementing spatial transcriptomics as an indispensable research tool. Additionally, growing interest in tissue heterogeneity has spurred demand for advanced library preparation solutions and novel sequencing workflows that retain spatial context. Tools such as CRISPR/Cas9 have propelled functional genomics into spatial domains, while the increasing application of in situ sequencing is expected to accelerate growth, underscoring the segment’s strategic importance in both research and clinical diagnostics.

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Product Insights

The consumables segment led the market in 2022 with a dominant 52.6% revenue share, largely driven by their recurring use across spatial genomics workflows and the expansive offerings from key industry players. These consumables play a critical role in enabling accurate spatial profiling and are essential for studying complex biological systems like tumor microenvironments, where spatial distribution of gene expression offers crucial insights. Simultaneously, the software segment is projected to witness the fastest growth through 2028, fueled by increasing demand for sophisticated bioinformatics tools capable of managing and analyzing large-scale spatial data. As cancer prevalence rises—highlighted by 1.9 million new cases in the U.S. in 2021 alone—demand for spatial consumables is expected to increase significantly. Furthermore, strategic collaborations, such as the Oxford Nanopore and 10x Genomics partnership to co-develop consumables for spatial and single-cell sequencing, are set to drive innovation and expand the segment’s reach.

End-use Insights

Translational research accounted for the largest share of end-use revenue in 2022 at 60.2%, as spatial omics technologies increasingly empower researchers to dissect disease mechanisms at a cellular and molecular level, aiding in the development of novel diagnostic and therapeutic approaches. These tools provide unmatched resolution in understanding cell organization, molecular interactions, and gene expression patterns across tissues, which is especially critical in fields like oncology, neurology, and immunology. Academic institutions also experienced significant revenue growth due to rising adoption of spatial genomics in large-scale research initiatives, such as the Human Cell Atlas and dedicated centers like the Children’s Hospital of Philadelphia’s Center of Spatial and Functional Genomics. These technologies have revolutionized gene expression studies and are becoming indispensable for advancing knowledge of diseases like cancer, diabetes, and Alzheimer’s at the tissue-specific level.

Regional Insights

North America dominated the spatial genomics and transcriptomics market in 2022 with a 44.47% revenue share, supported by strong federal funding, cutting-edge research programs like the NIH’s Single Cell Analysis initiative, and rapid clinical integration of spatial technologies. The region benefits from a robust infrastructure for genomics R&D and ongoing collaborations aimed at advancing precision medicine, exemplified by Illumina and Genetic Alliance’s $120 million initiative to promote genetic equity. Meanwhile, Asia Pacific is expected to see the fastest growth through 2030 due to increasing investments in life sciences and high-impact collaborations between local research institutions and global biotech companies. A notable example includes the 2022 partnership between MGI, MiRxes, and BGI’s Stereo-Seq platform, establishing a spatial multiomics hub at Singapore’s Biopolis to enhance regional research capabilities and fuel innovation in genomic science.

Market Snapshot